It is possible to have multiple base prices in Magento but you need to set up different websites:

Step 1. In Magento product price scope can be kept either global or per website, so you can have only one base price currency for a website. To set the Catalog Price Scope to website log into the Admin and go to System – > Configuration -> Catalog -> Price

Step 2. Set up multiple websites in Configuration > Manage Stores (you will need to creat a website/view and store for your new shop)

Step 3. Set the pricing for each one in Configuration > {switch store} > Currency Set up

Displaying configurable products with options on one page can be problem because Javascript in Magento is setup to work only with one configurable product.
You can write your own Javascript or U can reuse Magento code.

To accomplish that we need to modify product Javascript (js/varien/product.js) and configurable (catalog\product\view\type\options\configurable.phtml) select element template.

In configurable.phtml call our new JS class (we will create that class later in article) and add product id to configurable select element class.

Gone are the days when you have to setup separate E-commerce scripts to manage & run multiple online stores. Magento makes new store creation extremely easy for the store owners so that they can have as many stores as they like still maintaining one backend (admin panel). If you are new to Magento then this tutorial will require you to read the instructions very carefully. You can create multiple stores with other E-commerce software as well i.e. osCommerce, X-Cart, Zen Cart or Miva but to have multiple stores you need to add few plugins, addons and invest in hiring a full time programmer which is painful. A single Magento installation will be enough to run multiple stores having different domain names, different IP’s and different Security certificate. You can optionally setup single checkout for each store as well.

Choose Your Preferred URL Structure

Choosing a URL structure for your individual store is your own personal choice. You can install two different stores on same domain name under different directories ie. Mystore.com/women & Mystore.com/men. You can also use single Magento installation to host two or more stores each sharing same Magento backend but pointing to different domain names as well i.e. womenstores.com & mensstore.com. Similarly you can setup more than one Magento powered stores in sub-domains i.e. women.mystore.com & men.mystore.com

This article will describe quickest way how to use and configure one Magento installation on different domains.
Point here is what do you want to have on that different domains, for example you want to have chosen categories/products on one domain and the other one will be on different language.
First you figure that and then go to configuration.

So for each domain you need to create webiste in main Magento admin installation:
System > Manage Stores > Create Website

For Name: you enter name of you desired domain (“my.website.com”)
For Code: you will enter identifier for that domain (“my_website_com”)

After that you will go to:
System > Manage Stores > Create Store